1
Product and feeder trial
Provide representative tablets, coatings, dust behavior, orientation constraints and allowable cosmetic defects. Feeding performance must be demonstrated with the real product.
Tablet blister projects for pharmaceutical production
Pharmaceutical Tablet Blister Packing Machine
Configure the forming material, tablet feeder, pack format, inspection, reject logic and documentation around your product and URS—not around an unsupported headline speed.
01Start with representative tablets, lidding and forming material, and the approved blister drawing.
02Match the platform to forming area, stroke, material path, inspection and downstream interface.
03Define FAT acceptance using good packs, rejects, alarms and retained evidence.
DPP-260/360KFlat-plate medium-speed reference platform
DPH-380BRoller-plate high-speed reference platform
PVC/Alu · Alu/AluFinal material scope is model and tooling dependent
Project definition
Specify the pack before selecting the machine
A pharmaceutical tablet blister project is a chain of connected decisions. Product behavior, forming material, cavity geometry, feeding, inspection and downstream handling must be agreed as one scope.
2
Blister and material definition
Submit the approved pack drawing, cavity layout, forming web, lidding foil, print registration and batch-code requirements. The drawing controls tooling and feed stroke.
3
Accepted output definition
Agree what counts as a good blister: correct tablet count, sealed web, legible code, correct cut, controlled reject and stable transfer to the next machine.
Process architecture
Six stations that must operate as one blister process
The exact hardware changes by platform and format, but every proposal should define these functional boundaries and the evidence used to accept them.
1
Unwind
Control the forming web and lidding material supply, alignment and shortage response.
2
Form
Heat and form cavities to the approved drawing without thinning or deformation outside acceptance.
3
Feed
Place the specified tablet count into the correct cavities while controlling dust and damage.
4
Inspect
Detect the agreed missing-product and web conditions and route rejects as specified.
5
Seal and code
Apply the lidding web, seal within the approved window and mark required batch information.
6
Cut and discharge
Cut to format, keep the blister controlled and transfer it to collection or downstream equipment.
Procurement checkpoint: ask the supplier to mark every included sensor, reject path, interface signal, utility and format part on the line layout and quotation.
Published reference platforms
Compare verified machine ranges—not invented package claims
The values below come from the available HIJ DPP-260/360K and DPH-380B technical documents. Final configuration remains subject to product, tooling, material and contract review.
| Decision field | DPP-260/360K reference | DPH-380B reference | What the buyer must confirm |
|---|---|---|---|
| Platform | Flat-plate medium-speed Alu/PVC and Alu/Alu | High-speed roller-plate Alu/PVC and Alu/Alu | Product, material path and required good output |
| Published blanking range | Up to 40 cycles/min for the stated 57 × 80 mm × 4 reference format | 40–180 cycles/min | Do not convert cycles to saleable blisters without the approved format |
| Feed stroke | 40–120 mm | 40–240 mm | Approved blister drawing and print pitch |
| Maximum forming area | 245 × 112 mm | 260 × 240 mm | Cavity layout, trim and registration allowance |
| Published forming depth | 12 mm for Alu/Alu; special configuration noted up to 25 mm | 14 mm | Tablet envelope plus forming-material limits |
| Published total power | 11 kW | 25 kW | Site voltage, frequency and installed utility margin |
| Published air demand | 0.25 m³/min | 0.6 m³/min | Pressure, air quality and simultaneous demand |
| Published footprint | 4470 × 1100 × 1740 mm | 5400 × 1380 × 2100 mm with hopper | Access, maintenance clearance and material flow |
Forming and lidding material
Choose material from the pack specification and stability requirement
The machine should reproduce an approved packaging system. Material selection belongs in the product and package-development process; the equipment proposal must then reflect forming method, web width, heating, sealing and tooling.
PVC/Alu
Confirm PVC thickness, web width, lidding foil specification, print registration, cavity depth and sealing-window evidence.
PVDC-based forming web
Confirm the exact laminate construction and forming/sealing behavior with the material supplier and representative reels.
Alu/Alu
Confirm cold-form cavity geometry, material draw, forming depth, web width and format efficiency before selecting the platform.
Material evidence to send with the RFQ
- Approved packaging-material specification and supplier data
- Forming and lidding reel samples in the intended width
- Pack drawing with cavity, pitch, trim and code area
- Sealing and integrity acceptance method
- Storage and shelf-life requirement defined by your product team
Inspection, reject and changeover
Define control functions as testable requirements
“Inspection included” is too vague for a purchase order. State the defect, detection point, machine response, reject route, challenge method and retained evidence.
Verified DPP-260/360K functions
- Detection and removal device for missing-product blisters
- Automatic stop/alarm response for depleted PVC
- Adjustable 40–120 mm feed stroke
- Modular station structure and tool-free handle-lock mold change described in the source document
- Air-cushion heat-seal lift response when stopped
Verified DPH-380B functions
- Camera-detection system with independent display
- Automatic stop for material shortage and abnormal tablet obstruction
- Servo-controlled traction and reject-transfer functions described in the source document
- Recipe storage for multiple product specifications
- Separate station drives and cooling provisions described for the heat-seal system
URS and FAT evidence
Make the quotation comparable and the FAT measurable
Use one shared input pack so every supplier prices the same scope and every FAT witness evaluates the same acceptance conditions.
Required RFQ inputs
- Tablet drawing, samples, coating and dust behavior
- Approved blister drawing and pack count
- Forming/lidding material specifications and reels
- Required accepted output and shift pattern
- Inspection, reject and batch-code requirements
- Utilities, room access and downstream interface
- Required documentation and language
Minimum FAT evidence
- Run with nominated product, tooling and packaging material
- Good-pack count against the agreed acceptance window
- Missing-product and abnormal-condition challenges
- Alarm, stop and restart response records
- Reject segregation and reconciliation evidence
- Seal, code, cut and visual acceptance samples
- Open-item list with owner and closure evidence
Validation boundary: HIJ can engineer equipment and documentation to support your DQ/IQ/OQ/PQ process. Your quality unit remains responsible for approving protocols, acceptance criteria and release decisions.
Frequently asked questions
Pharmaceutical tablet blister machine FAQ
Practical answers for procurement, production, engineering and validation teams.
What information is needed to quote a pharmaceutical tablet blister packing machine?
Provide representative tablets, the approved blister drawing, forming and lidding material specifications, target accepted output, inspection and reject requirements, utilities, downstream interfaces, and the required documentation scope. Without these inputs, suppliers are not quoting the same project.
How should machine speed be compared?
Compare accepted good blisters per minute at the nominated format, product, material and inspection load. A cycles-per-minute value is not directly comparable until the number of blisters per cycle and the agreed efficiency and reject definitions are stated.
Can one platform run PVC/Alu and Alu/Alu formats?
The available HIJ technical documents describe Alu/PVC and Alu/Alu capability on the referenced platforms, but the final scope depends on the selected model, forming station, web width, tooling and material. Confirm both formats explicitly in the quotation and FAT scope.
What inspection functions should be specified?
Define the defect to detect, the inspection location, the required machine response, the physical reject path, reconciliation method and FAT challenge. Typical project requirements may include missing-product detection, material-shortage response, code verification and reject confirmation.
Does the machine itself become FDA approved or GMP certified?
No. Equipment is not approved by the FDA as a pharmaceutical product, and compliance depends on the installed system, procedures, records and the manufacturer’s quality system. The machine and documentation can be engineered to support the customer’s cGMP and validation requirements.
What should be tested during FAT?
Run the nominated product, tooling and packaging materials under agreed conditions. Record good output, seal and cut quality, inspection challenges, reject segregation, alarms, stops and restarts, code quality, retained samples and every open item requiring closure.
Project inquiry
Configure the machine around your tablet and pack
Send samples, the blister drawing, packaging-material specifications, required good output, inspection scope and documentation needs. HIJ can return a project-specific equipment and FAT scope for review.