WHO GMP · cGMP · CE Certified Manufacturer
Blister Packaging Solutions European Quality · Smart Pricing · GMP Certified
Complete pharmaceutical blister packaging machines from HIJ Machinery, China. Engineered for tablets, capsules, softgels, liquids and medical devices — operating at 100–800 blisters/min with full DQ/IQ/OQ/PQ documentation.
WHO GMP
21 CFR Part 11 Ready
21 CFR Part 11 Ready
What Is Blister Packaging?
Blister packaging is a pharmaceutical packaging method that uses thermoformed plastic (PVC, PVDC) or cold-formed aluminum (Alu-Alu) to create individual sealed cavities holding tablets, capsules, or other unit-dose products. Each cavity is sealed with aluminum lidding foil — providing tamper evidence, dose accuracy, and protection from moisture, light, and oxygen. HIJ Machinery manufactures complete blister packaging lines in Wenzhou, China, compliant with WHO GMP TRS 961, cGMP 21 CFR Parts 210/211, and CE Machinery Directive 2006/42/EC.
Output Speed
100–800
blisters / minute
blisters / minute
Material Types
PVC · PVDC
Alu-Alu
Alu-Alu
Compliance
WHO GMP
cGMP · CE · 21 CFR
cGMP · CE · 21 CFR
Lead Time
12–16
weeks FOB Wenzhou
weeks FOB Wenzhou
HIJ Blister Packaging — Quick Specs
- Speed Range100–800 blisters/min
- Forming MaterialPVC / PVDC / Alu-Alu
- Lidding FoilHard Aluminum 20–30μm
- ComplianceWHO GMP / cGMP / CE
- ValidationDQ/IQ/OQ/PQ Included
Global Service Reach
- Markets Served30+ Countries
- Pharma Factories100+ Worldwide
- On-site SupportAvailable Globally
- Response TimeWithin 24 Hours
- Contact[email protected]
HIJ Blister Packaging Machine Series
From semi-automatic R&D units to high-speed cGMP production lines — find the right blister packaging solution for your product type and output volume.
Best Seller
Pharmaceutical Blister Packaging Machine
For tablets, capsules and softgels. WHO GMP & cGMP compliant. Ideal for medium-to-high volume pharmaceutical production.
Speed120–300/min
MaterialPVC / PVDC / Alu-Alu
ComplianceWHO GMP · CE
High Barrier
Alu-Alu Cold Form Blister Machine
Maximum barrier protection for moisture/oxygen-sensitive drugs. Effervescent tablets, hygroscopic APIs, unstable molecules.
Speed100–300/min
FormingCold Form Aluminum
Barrier100% Moisture/O₂
High Speed
DPP-260 Fully Automatic Blister Machine
Industrial-grade automatic blister line for high-volume production. Servo control, vision inspection, integrated rejection system.
Speed300–600/min
ControlServo + PLC
Compliance21 CFR Part 11
Specialty
Liquid Blister Packaging Machine
For honey, syrup, eye drops, jam and oral liquids. Precision filling nozzles with anti-drip and volume control.
Speed40–120/min
Fill Range0.5–25 ml
ApplicationLiquid / Semi-liquid
Food Grade
Chocolate Blister Packing Machine
Food-grade design (AISI 316L stainless steel) for chocolate, candy, truffles and confectionery products.
Speed60–200/min
MaterialPVC / PET / Alu
CertificationFDA Food Grade
Medical Device
Syringe Blister Packaging Machine
Designed for pre-filled syringes and medical devices. Tyvek lidding compatible, cleanroom-ready construction.
Speed60–150/min
LiddingTyvek / Alu Foil
StandardISO 13485 Ready
PVC vs PVDC vs Alu-Alu Blister Packaging
Choosing the right blister forming material is critical for product stability and regulatory compliance. Here's the engineering comparison.
| Property | PVC (Standard) | PVDC-Coated PVC | Alu-Alu (Cold Form) |
|---|---|---|---|
| Moisture Barrier (WVTR) | Low (3.0 g/m²/day) | Medium (0.5 g/m²/day) | Excellent (0.0 g/m²/day) |
| Oxygen Barrier | Low | High | Complete |
| Light Protection | None (transparent) | Partial | 100% Opaque |
| Forming Process | Thermoforming | Thermoforming | Cold Forming |
| Cost Index | Lowest | Medium | Highest |
| Machine Speed | Up to 800/min | Up to 600/min | 100–300/min |
| Best For | Standard tablets, OTC drugs | Moisture-sensitive tablets | Hygroscopic APIs, effervescents |
GMP Compliance & Validation Support
Every HIJ blister packaging machine is engineered to meet international pharmaceutical regulatory standards. Complete validation documentation included with every delivery.
Regulatory Standards Met
- WHO GMP: Technical Report Series No. 961, Annex 6
- US cGMP: 21 CFR Parts 210 and 211
- Electronic Records: 21 CFR Part 11 (optional)
- EU GMP: EudraLex Volume 4
- CE Marking: Machinery Directive 2006/42/EC
- ICH Guidelines: Q7, Q9, Q10 aligned
Validation Documentation Package
- DQ: Design Qualification protocol & report
- IQ: Installation Qualification with checklists
- OQ: Operational Qualification test scripts
- PQ: Performance Qualification with sampling plan
- FAT/SAT: Factory & Site Acceptance Testing
- URS: User Requirement Specification template
WHO GMP Requirements for Blister Packaging Equipment
According to WHO Technical Report Series No. 961, Annex 6, pharmaceutical blister packaging equipment must meet the following requirements:
- Material compliance: All product contact surfaces shall be stainless steel AISI 316L or equivalent, non-reactive, non-absorptive.
- Cleanability: Equipment design must allow for thorough cleaning and, where applicable, sterilization (CIP/SIP capability or easy disassembly).
- Documentation: Complete equipment qualification records (DQ/IQ/OQ/PQ) shall be maintained throughout the equipment lifecycle.
- Calibration: All measuring instruments (temperature, pressure, speed, dose volume) shall be within documented calibration schedules.
- Change control: Documented procedures shall govern all equipment modifications, including parts replacement and software updates.
- Tamper evidence: Blister seal integrity must be verifiable through inline vision inspection or sampling test protocols.
HIJ Machinery designs all blister packaging equipment to fully meet these requirements. Complete validation documentation package — including DQ/IQ/OQ/PQ protocols, calibration certificates, material certificates of conformity, and change control templates — is provided with every machine delivery.
Blister Packaging Machine Price Guide 2026
Transparent pricing tiers based on output speed, compliance level, and forming technology. All prices FOB Wenzhou, China.
Entry Level
Semi-Automatic
50–100 blisters/min
USD 15,000 – 35,000FOB Wenzhou · CE Included
- Manual material loading
- PVC thermoforming
- Basic CE certification
- R&D / Small batch ideal
Most Popular
Automatic Standard
100–300 blisters/min
USD 40,000 – 120,000WHO GMP + DQ/IQ Included
- Servo motor control
- PVC / PVDC capability
- WHO GMP compliant
- Vision inspection optional
High Performance
High-Speed cGMP
300–600 blisters/min
USD 130,000 – 280,00021 CFR Part 11 Ready
- Full servo + PLC
- cGMP 21 CFR compliant
- Inline vision + rejection
- Complete DQ/IQ/OQ/PQ
Specialty
Alu-Alu Cold Form
100–300 blisters/min
USD 80,000 – 200,000Highest Barrier · GMP
- Cold forming station
- Complete moisture barrier
- For hygroscopic drugs
- Full validation included
💡 European-Standard Quality at 30–40% Below EU Market Pricing.
All prices include CE certification and standard DQ/IQ documentation. Optional features (vision inspection, serialization, 21 CFR Part 11, integration with cartoning lines) priced separately. Contact [email protected] for detailed quotation tailored to your URS.
All prices include CE certification and standard DQ/IQ documentation. Optional features (vision inspection, serialization, 21 CFR Part 11, integration with cartoning lines) priced separately. Contact [email protected] for detailed quotation tailored to your URS.
Why Global Pharma Manufacturers Choose HIJ
European-standard engineering. Smart pricing. Complete compliance support. The reason 100+ pharmaceutical factories in 30+ countries trust HIJ.
20+
Years of Pharmaceutical Expertise
Founder Forester Xiang has 20+ years in pharmaceutical machinery design, manufacturing, and validation — having audited 100+ pharma factories worldwide.
30–40%
Below European Pricing
Same European-standard engineering. Smarter pricing. Save USD 50,000–150,000 per line vs. European brands without compromising compliance or quality.
100%
GMP Documentation Included
Complete DQ/IQ/OQ/PQ validation package with every machine. URS-driven engineering. FAT/SAT support. On-site validation assistance available globally.
Chinese vs European Blister Packaging Machines
Honest comparison from 20+ years of industry experience
| Criteria | European Brands | Other Chinese Suppliers | HIJ Machinery |
|---|---|---|---|
| Engineering Quality | Excellent | Inconsistent | European-standard ✓ |
| Price Range (Standard Line) | USD 200,000–500,000 | USD 25,000–80,000 | USD 40,000–280,000 |
| Lead Time | 20–30 weeks | 8–14 weeks | 12–16 weeks |
| GMP Documentation | Complete | Partial / Generic | Complete & URS-aligned ✓ |
| Asia-Pacific Support | Limited / Distributor | Local but inconsistent | Direct & Global ✓ |
| On-site Validation Support | Premium charge | Rare | Available globally ✓ |
| 21 CFR Part 11 Compliance | Standard | Often unavailable | Available ✓ |
Blister Packaging Applications
HIJ blister packaging machines serve diverse industries with proven solutions for tablets, capsules, liquids, food, and medical devices.
20+ Years
Pharma Machinery Expertise
Forester Xiang
FOUNDER & CEO · HIJ MACHINERY
With 20+ years of pharmaceutical machinery expertise, Forester Xiang has personally audited 100+ pharmaceutical manufacturing facilities across India, Bangladesh, Vietnam, Nigeria, Egypt, Brazil, Germany, and 30+ other countries.
His deep technical knowledge spans WHO GMP, US cGMP, FDA 21 CFR Parts 210/211/11, EU GMP, and ICH guidelines — making HIJ Machinery the go-to partner for pharmaceutical manufacturers worldwide who need European-standard equipment without European pricing.
The biggest gap I see in pharmaceutical blister packaging globally is not the machinery itself — it's the validation documentation and change control procedures. A machine is only as compliant as its paperwork. That's why every HIJ blister machine ships with complete DQ/IQ/OQ/PQ documentation, every single time.
100+
Pharma Factories Audited
30+
Countries Visited
20+
Years Industry Experience
Trusted by Pharma Manufacturers Worldwide
Real projects. Real factories. Real compliance results.
100+
Pharma Factories
30+
Countries Served
500+
Lines Delivered
24h
Response Time
🇮🇳
500K Tablets/Day Pharma Blister Line
Complete WHO GMP-validated tablet blister packaging line delivered to a major pharmaceutical manufacturer in Hyderabad. Integrated with cartoning and case packing.
🇳🇬
WHO GMP Turnkey Packaging Project
Full turnkey blister + cartoning line for a Lagos-based pharmaceutical group. URS-driven design, on-site FAT/SAT, complete IQ/OQ/PQ validation support.
🇻🇳
cGMP Upgrade — Alu-Alu Cold Form
Alu-Alu cold form blister machine upgrade for moisture-sensitive APIs at a Ho Chi Minh City facility. 21 CFR Part 11 compliant electronic records.
🇪🇬
Effervescent Tablet Blister Line
Specialty Alu-Alu blister line for effervescent vitamin C tablets. Custom moisture-controlled environment integration. Full validation package delivered.
🇧🇩
High-Speed Capsule Blister Production
600 blisters/min capsule packaging line for a Dhaka pharmaceutical exporter. Integrated vision inspection, automatic rejection, batch printing system.
🇧🇷
ANVISA-Compliant Pharma Line
Complete pharmaceutical blister + cartoning line meeting Brazilian ANVISA regulations. On-site validation support and operator training included.
Frequently Asked Questions
Answers to the most common questions from pharmaceutical buyers worldwide.
What is blister packaging?
Blister packaging is a pharmaceutical packaging method that uses thermoformed plastic (PVC, PVDC) or cold-formed aluminum (Alu-Alu) to create individual sealed cavities holding tablets, capsules, or other unit-dose products. Each cavity is sealed with aluminum lidding foil, providing tamper evidence, dose accuracy, and protection from moisture, light, and oxygen.
How much does a blister packaging machine cost?
Blister packaging machine prices range from USD 15,000 for semi-automatic units to USD 280,000 for high-speed cGMP lines. Semi-automatic (50–100/min): USD 15,000–35,000. Automatic standard (100–300/min): USD 40,000–120,000. High-speed cGMP (300–600/min): USD 130,000–280,000. Alu-Alu cold form (100–300/min): USD 80,000–200,000. All FOB Wenzhou, including CE certification and standard DQ/IQ documentation.
What is the difference between PVC, PVDC, and Alu-Alu blister packaging?
PVC offers basic moisture barrier and is the most economical option for standard tablets. PVDC-coated PVC provides higher moisture and oxygen barrier for moisture-sensitive products. Alu-Alu (cold-form aluminum) delivers the highest barrier protection — completely opaque, fully impermeable to moisture, oxygen, and light — ideal for hygroscopic drugs, effervescent tablets, and unstable APIs.
Are HIJ blister packaging machines WHO GMP and cGMP certified?
Yes. All HIJ blister packaging machines comply with WHO GMP (TRS No. 961, Annex 6), US cGMP (21 CFR Parts 210 and 211), EU GMP (EudraLex Volume 4), and CE Marking under Machinery Directive 2006/42/EC. Optional 21 CFR Part 11 electronic records compliance is available. Complete DQ/IQ/OQ/PQ validation documentation provided with every machine.
How long does delivery take from HIJ Machinery?
Standard lead time is 12–16 weeks from order confirmation, FOB Wenzhou, China. Complex turnkey packaging lines: 20–26 weeks. Rush production available on select models in 8–10 weeks subject to availability. Lead time includes manufacturing, factory acceptance testing (FAT), and pre-shipment inspection.
Does HIJ provide IQ OQ PQ validation documentation?
Yes. HIJ Machinery provides complete validation documentation including Design Qualification (DQ), Installation Qualification (IQ), Operational Qualification (OQ), and Performance Qualification (PQ) protocols. All documentation is prepared in accordance with WHO GMP, cGMP, and ICH Q7 guidelines. On-site validation support and FAT/SAT services available globally.
What products can HIJ blister packaging machines handle?
HIJ blister packaging machines handle a wide range of products: pharmaceutical tablets, hard and soft gelatin capsules, softgels, effervescent tablets, lozenges, suppositories, medical devices, pre-filled syringes, chocolate and confectionery, liquid products (honey, syrup, jam), and nutraceutical supplements. Quick mold changeover (typically under 30 minutes) supports multi-product lines.
Is HIJ Machinery a manufacturer or trading company?
HIJ Machinery is a direct manufacturer with its own factory in Wenzhou, Zhejiang Province, China. Founded by Forester Xiang with 20+ years of pharmaceutical machinery expertise, HIJ has served 100+ pharmaceutical manufacturing facilities across 30+ countries. All design, manufacturing, testing, and validation are performed in-house.
What output speed do I need for my production?
Output speed depends on annual production volume. Under 10M units/year: semi-automatic or 100/min sufficient. 10–50M units/year: 200–300/min automatic recommended. 50–200M units/year: 400–600/min high-speed line. Over 200M units/year: 600–800/min or multiple parallel lines. HIJ engineers can size your line precisely based on URS.
Does HIJ provide global after-sales support?
Yes. HIJ provides global after-sales support including on-site installation and commissioning, operator training, IQ/OQ/PQ validation support, remote diagnostics, spare parts supply, and 24-hour technical response. HIJ has supported pharmaceutical manufacturers in India, Bangladesh, Vietnam, Nigeria, Egypt, Brazil, Mexico, Saudi Arabia, and 20+ other countries.
Ready to Upgrade Your Blister Packaging Line?
Join 100+ pharmaceutical manufacturers in 30+ countries who chose HIJ for European-standard blister packaging machines at smart pricing. Get your custom quote within 24 hours.
WHO GMP Certified
21 CFR Part 11 Ready
CE Compliant
DQ/IQ/OQ/PQ Included
24-Hour Response
Global Support
HIJ Machinery (Wenzhou) · Pharmaceutical Blister Packaging Machinery Manufacturer
Website: hijpackingmachine.com · Founder: Forester Xiang (20+ years pharmaceutical machinery expertise)
Specialization: Blister packaging machines, capsule filling machines, cartoning machines, turnkey pharmaceutical packaging lines
Compliance: WHO GMP TRS 961 · cGMP 21 CFR Parts 210/211 · CE Machinery Directive 2006/42/EC · EU GMP EudraLex Volume 4
Website: hijpackingmachine.com · Founder: Forester Xiang (20+ years pharmaceutical machinery expertise)
Specialization: Blister packaging machines, capsule filling machines, cartoning machines, turnkey pharmaceutical packaging lines
Compliance: WHO GMP TRS 961 · cGMP 21 CFR Parts 210/211 · CE Machinery Directive 2006/42/EC · EU GMP EudraLex Volume 4