GGS-118 P5 · BFS Form-Fill-Seal
Plastic Ampoule Oral Liquid Filling & Sealing Machine
An automatic blow-fill-seal (BFS) machine that forms, fills, and hermetically seals single-dose plastic ampoules in one continuous, fully enclosed cycle — engineered for WHO-GMP oral liquids, liquid supplements, and monodose cosmetic serums with zero secondary contamination.
WHO-GMP Ready
Single-Dose · Anti-Contamination
SUS 316L Contact Parts
CE Marked
0.3–200mlFill Range
5Filling Heads
±1%Dosing Accuracy
ISO 5Optional Clean Zone
15+ Years OEM Manufacturing
ISO 9001:2015 Quality System
Exported to 40+ Countries
Lifetime Engineering Support
Overview
What Is a Plastic Ampoule Oral Liquid Filling & Sealing Machine?
A plastic ampoule oral liquid filling and sealing machine is an automatic blow-fill-seal (BFS) system that converts pharma-grade PE/PP film into individual plastic ampoules, fills each with a precise dose of liquid, and heat-seals it — all inside one sealed, sterile-capable chamber. Because the ampoule is formed, filled, and closed in a single uninterrupted cycle, the product never touches the open environment, eliminating the cross-contamination risk of pre-formed bottles or multi-dose containers.
The HIJ GGS-118 P5 is built for single-dose (monodose) oral liquids — pharmaceutical syrups and solutions, probiotic and enzyme shots, liquid vitamin supplements, and high-value cosmetic serums and essences. It delivers tamper-evident, snap-off ampoules at up to ~100 units/min (10 ml) with ±1% dosing accuracy, and is configured to WHO-GMP and cGMP-ready standards out of the box.
Technical Data
GGS-118 P5 — Key Specifications
Standard configuration. Heads, ampoule format, and clean-room class are tailored to your product and output target.
| Model | GGS-118 (P5) |
|---|---|
| Container Type | Plastic ampoule / monodose vial (PE or PP, BPA-free) |
| Filling Range | 0.3 ml – 200 ml (2 / 5 / 10 / 20 ml typical) |
| Filling Heads | 5 (servo-metered, individually adjustable) |
| Output | Up to ~100 ampoules/min at 10 ml (≈6,000/h; model-dependent) |
| Dosing Accuracy | ±1% |
| Contact Materials | SUS 316L (product path) / SUS 304 (frame) |
| Control System | PLC + 7" HMI touchscreen, recipe storage |
| Sealing | Integrated heat-form sealing + tamper-evident snap tab |
| Coding | Hot-stamp / embossed batch & expiry on strip (optional inkjet) |
| Clean Zone | Optional Class 100 (ISO 5) laminar flow over fill/seal |
| Power | 3-phase 380V / 50–60Hz (configurable) |
| Compliance | WHO-GMP · cGMP-ready · CE · ISO 9001:2015 build |
Why This Machine
Built for Sterile, Single-Dose Production
Six engineering choices that protect your product, your batch records, and your margin.
Zero Secondary Contamination
Form, fill, and seal happen in one enclosed cycle — no pre-made containers, no open transfer, no human contact with the product.
±1% Servo Dosing
Independent servo pumps on each head hold fill volume tight across the full 0.3–200 ml range, cutting overfill giveaway.
SUS 316L Product Path
Every wetted surface is pharma-grade 316L stainless — corrosion-resistant, CIP-friendly, and safe for actives and serums.
ISO 5 Clean Option
Add a Class 100 laminar-flow hood over the filling and sealing zone for sterile and ophthalmic-grade products.
Tamper-Evident by Design
Snap-off, single-use ampoules are inherently tamper-evident — ideal for monodose pharma and premium cosmetics.
PLC + HMI Recipe Control
Store product recipes, switch formats fast, and export batch data — supporting cGMP documentation and audit trails.
Process
How the Blow-Fill-Seal Cycle Works
Five continuous stages, fully enclosed — from raw film to a finished, coded ampoule strip.
Form
Pharma-grade PE/PP film is heated and blow-molded into ampoule cavities on the strip.
Fill
5 servo nozzles dose the exact liquid volume into each cavity at ±1% accuracy.
Seal
Cavities are immediately heat-sealed, creating a hermetic, tamper-evident closure.
Code
Batch number and expiry are embossed or printed onto the strip in line.
Cut
Strips are trimmed to your card count and discharged ready for cartoning.
Applications
One Platform, Pharma to Premium Cosmetics
Wherever a precise, contamination-free single dose matters.
Pharmaceutical Oral Liquids
Syrups, oral solutions, antitussives, electrolyte and rehydration doses — WHO-GMP single-dose packaging.
Liquid Supplements & Probiotics
Vitamin shots, enzyme and probiotic drinks, herbal extracts — stable, portable single servings.
Cosmetic Serums & Essences
Monodose ampoule serums, hyaluronic essences and brightening boosters with luxury, fresh-dose appeal.
Compliance & Quality
Designed Around Global Regulatory Expectations
HIJ does not "certify" your product — but we build the equipment so your validation passes the first time.
WHO-GMP & cGMP-Ready
Sanitary 316L design, documented build, and audit-friendly batch control.
ISO 22716 (Cosmetic GMP)
Hygienic configuration suited to cosmetic serum and essence production.
CE Marked
Conformity for safe machinery operation across applicable markets.
IQ/OQ/PQ Support
Validation documentation package and FAT/SAT support on request.
Related Equipment
Complete Your Liquid & Cosmetic Line
Part of the full cosmetic packaging machines range. Pair the GGS-118 P5 with upstream and downstream equipment for a turnkey line.
Cosmetic Ampoule Filling Machine
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Single-use sachets for liquids, gels and samples.
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Pricing & ROI Guide
Budget ranges and payback for cosmetic packaging machinery.
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FAQ
Frequently Asked Questions
What is the difference between BFS plastic ampoules and glass ampoules?
Blow-fill-seal (BFS) plastic ampoules are formed, filled, and sealed in one enclosed cycle from PE/PP film, so the liquid never contacts the open environment. They are unbreakable, lighter, snap-open without glass shards, and lower-cost at volume — while still delivering tamper-evident, single-dose protection comparable to glass.
What fill volumes and output can the GGS-118 P5 handle?
The standard machine fills 0.3 ml to 200 ml, with 2, 5, 10 and 20 ml ampoules being most common. The five-head configuration reaches roughly 100 ampoules per minute at 10 ml (about 6,000/hour); higher outputs are available with additional heads and format tooling.
Is the machine suitable for sterile or pharmaceutical oral liquids?
Yes. The product path is SUS 316L and the fill/seal zone can be fitted with a Class 100 (ISO 5) laminar-flow hood. The build is configured to WHO-GMP and cGMP expectations, and we supply IQ/OQ/PQ validation documentation to support your qualification.
Can it fill cosmetic serums and essences as well as medicine?
Absolutely. The same platform handles monodose cosmetic serums, hyaluronic essences and treatment boosters under ISO 22716 hygienic design. Single-dose ampoules give premium products a fresh, tamper-proof, "one application per ampoule" positioning.
What is the lead time and what support do you provide?
Typical lead time is 45–70 days depending on configuration and clean-room options. Every machine includes installation guidance, operator training, a spare-parts kit, and lifetime remote engineering support. Request a quote for a project-specific timeline.
Get Your Single-Dose Line Quoted Today
Tell us your product, fill volume, and target output — our engineers will return a tailored GGS-118 P5 configuration, turnkey scope, and price.